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Mathematics of DNA Structure, Function and Interactions

The IMA Volumes in Mathematics and its Applications 150

Erschienen am 25.02.2012, 1. Auflage 2014
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Bibliografische Daten
ISBN/EAN: 9781461424529
Sprache: Englisch
Umfang: xii, 356 S., 70 farbige Illustr., 356 p. 70 illus.
Einband: kartoniertes Buch

Beschreibung

InhaltsangabeNick Cozzarelli: A Personal Remembrance.- Mathematical Methods in Dna Topology: Applications to Chromosome Organization and Site-Specific Recombination.- Conformational Statistics of Dna and Diffusion Equations on The Euclidean Group.- Perspectives On DNA Looping.- Differences Between Positively and Negatively Supercoiled DNA that Topoisomerases May Distinguish.- Calibration of Tethered Particle Motion Experiments.- Difference Topology: Analysis of High-Order DNA-Protin Assemblies.- Useful Intrusions of DNA Topology Into Experiments on Protein-DNA Geometry.- Topological Analysis of DNA-Protein Complexes.- Closing the Loop on Protein-DNA Interactions: Interplay Between Shape and Flexibility in Nucleoprotein Assemblies Having Implications for Biological Regulation.- Four-Way Helical Junctions in DNA Molecules.- Micromechanics of Single Supercoiled DNA Molecules.- Flexibility Of Nucleosomes On Topologically Constrained DNA.- The Mathematics of DNA Sturcture, Mechanics, and Dynamics.- Paradox Regained: a Topological Coupling of Nuclesomal DNA Wrapping and Chromatin Fibre Coiling.- Statistical-Mechanical Analysis of Enzymatic Topological Transformations in DNA Molecules.

Autorenportrait

InhaltsangabeForeword.- Preface.- Nick Cozzarelli: A personal remembrance.- Mathematical methods in DNA topology: Applications to chromosome organization and site-specific recombination.- Conformational statistics of DNA and diffusion equations on the Euclidean group.- Perspectives on DNA looping.- Differences between positively and negatively supercoiled DNA that topoisomerases may distinguish.- Calibration of tethered particle motion experiments.- Difference topology: Analysis of high-order DNA-protein assemblies.- Useful intrusions of DNA topology into experiments on protein-DNA geometry.- Topological analysis of DNA-protein complexes.- Closing the loop on protein-DNA interactions: Interplay between shape and flexibility in nucleoprotein assemblies having implications for biological regulation.- Four-way helical junctions in DNA molecules.- Micromechanics of single supercoiled DNA molecules.- Flexibility of nucleosomes on topologically constrained DNA.- The mathematics of DNA structure, mechanics, and dynamics.- Paradox regained: a topological coupling of nucleosomal DNA wrapping and chromatin fibre coiling.- Statistical-mechanical analysis of enzymatic topological transformations in DNA molecules.- List of workshop participants.